A critical update on the immunopathogenesis of Stiff Person Syndrome.

Stiff person case misdiagnosed as conversion disorder: A case report

Background: Stiff person syndrome (SPS) is a rare neurological disease resulting in stiffness and spasm of muscles. It initially affects the axial muscles and then spread to limb muscles. Emotional stress exacerbated the symptoms and signs of the disease. The pathophysiology of the disease is caused by the decreased level of the glutamic acid decarboxylase (GAD) activity due to an autoantibody ...

Down Syndrome News and Update Volume 1 Number 2

[Stiff-person syndrome and other myelopathies constitute paraneoplastic neurological syndromes].

Stiff-person syndrome (SPS) is an autoimmune neurological disorder characterized by rigidity of the trunk and proximal limb muscles, intermittent superimposed spasms, and increased sensitivity to external stimuli. It has been more than 50 years since Moerch and Woltman reported the first 14 cases with this syndrome. During the last half century, many autoantibodies discovered, such as anti-glut...

Italian evidence-based guidelines for the management of influenza-like syndrome in adults and children.

Specific clinical practice recommendations for the management of influenza like-illness were developed by a national multidisciplinary panel (Guideline Development Group, GDG), and included in the update of the evidence-based clinical practice guideline: "Management of influenza-like syndrome" issued by the Italian National Guidelines System (SNLG May 2008). The methodological process included:...

Update in endocrinology - primary hyperaldosteronism - from secondary hypertension towards metabolic syndrome and beyond.

90 Maedica A Journal of Clinical Medicine, Volume 7 No.1 2012 Update in Endocrinology – Primary Hyperaldosteronism – From Secondary Hypertension Towards Metabolic Syndrome and Beyond Raluca-Alexandra TRIFANESCU, MD, PhDa,b; Catalina POIANA, MD, PhDa,b aEndocrinology Department, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania b“C.I.Parhon” National Institute of Endocrinolo...